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Wednesday: This One Day

In this roundup: British fascists rise, smart fridge serves porn, and a Zika overview.

Today’s featured short film by Crystal Moselle is about finding one’s tribe, finding one’s place, crossing the threshold to adulthood in the safety of community. Men may not feel this one as keenly as women will. Many of us are skating alone, running into obstacles set before us simply because we are. With a little support we could skate the world.

Love how Bikini Kill’s Rebel Girl plays us out at the end. That.

Brexit and broken

  • Ian Dunt: Tories have become Ukip (Politics.co.uk) — Op-ed looks at UK’s Conservative Party and its aggressive shift toward white nationalism.
  • No joke: UK’s Home Secretary sounds like a Nazi (LBC) — Seriously, read the link. Can’t tell Amber Rudd’s speech from Hitler’s Mein Kampf.
  • The Daily Mail as Tories’ key influencer (OpenDemocracy) — Anthony Barnett looks at the Mail’s succession to Murdoch’s right-wing propaganda mill. The Mail was one of the two largest traditional media influences on right-wing politicians and Brexit voters (the other being NewsCorp’s The Sun); an American parallel would be the shift in media influence on public opinion as Fox News gave way to a more rightest, Trump-friendly CNN. We don’t trust CNN any more than we do Fox, and the UK shouldn’t trust the Mail any more than it should trust The Sun.
  • Theresa May’s Tory Conference speech: fascism wearing a progressive mask (VICE) — May isn’t well known by either UK or US public; her speech this week to her own party gave us a better look at the politician, and she’s not at all pretty. May uses progressive language to make her case, but what she’s really pushing is outright fascism.
  • Unwinding a country rich in diversity (OpenDemocracy) — University of Birmingham lecturer and Oxford University research associate Nando Sigona looks at the United Kingdom as an EU citizen. How does a small but densely populated country — land mass the size of Michigan with a population equal to California and Texas combined — move away from the diversity which has made it rich for millennia? Imagine one of those U.S. states (MI/CA/TX) suddenly telling anyone not ‘native’ to that state to leave; what would it do to that state, let alone the people who must leave? It’s not tenable.
  • 80th anniversary of East London’s Battle of Cable Street (Guardian) — The British have apparently forgotten their history and are now condemned to repeat it. Who is this generation’s Oswald Mosely: Boris Johnson, Nigel Farage, Michael Gove, Theresa May? With attacks on immigrants increasing, the new blackshirts already make their presence known; they only lack a Mosely.

Still skeptical about Tories’ aggression? Just look at this tweet from Tim Colburne, former deputy chief of staff for LibDem Party’s Nick Clegg. This is not the work of a party working for business interests. We are watching a new Nazism rapidly engulfing the United Kingdom. I doubt it will remain united much longer at this pace.

Keep in mind some of the foreign workers and children the Tories (and Ukip) want identified are U.S. citizens.

Elsewhat, elsewhere

Cybernia, ho!

  • Ireland not happy about the Yahoo email scandal (ITNews-AU) — Ireland wants to know if Yahoo’s scanning emails on behalf of U.S. government compromises Irish citizens’ privacy. Germany’s Fabio de Masi, a member of the European Parliament, has also asked for more details. Yahoo’s scanning could put the brakes on a US-EU data sharing agreement.
  • Alleged terror plotter charged, had operating system in cufflink (Guardian) — Located in Cardiff, Wales, the accused also possessed a book on missile guidance and control; he was responsible for a blog with information about Isis and cyber-security guidance.
  • Smart refrigerator – now with Pornhub (The Register) — Didn’t manufacturers clue in about so-called smart refrigerators a couple years ago after they were hacked? Clearly not if it’s still possible to hijack displays on Internet of Things devices for porn.

Longread: Overview on Zika
This is a decent meta piece in Omni magazine. Article also points out simple preventive interventions to reduce Zika infections: air conditioning and window screens. Also suggests implementing these in Africa where other arbovirus diseases are endemic, like yellow fever, dengue, chikunguya as well as Zika — except AC will create a greater demand for electricity as well as manufacturing pressure for screens. Also doesn’t really deal with the fact more people are outside during daylight hours in warmer climates, and those who work outdoors (like farmers) have no choice. More comprehensive research on arboviruses is needed and work toward vaccines is probably cheaper, faster, and less taxing to the environment than scaling up electricity and manufacturing. Worth a read if flawed.

Phew. That’s enough for today. Thankfully it’s downhill from here. Catch you later!

Thursday: Alien Occupation

Since I missed a Monday post with a movie clip I think I’ll whip out a golden oldie for today’s post.

This movie — especially this particular scene — still gets to me 37 years after it was first released. The ‘chestburster’ as scene is commonly known is the culmination of a body horror trope in Ridley Scott’s science fiction epic, Alien. The horror arises from knowing something happened to the spacecraft Nostromo’s executive officer Kane when a ‘facehugger’ leapt from a pod in an alien ship, eating through his space helmet, leaving him unresponsive as long as the facehugger remained attached to his face. There is a brief sense of relief once the facehugger detaches and Kane returns to consciousness and normal daily functions. But something isn’t right as the subtle extra scrutiny of the science officer Ash foreshadows at the beginning of this scene.

Director Ridley Scott employed a different variant of body horror in his second contribution to the Alien franchise, this time by way of a xenomorph implanted in her mimicking pregnancy in scientist Shaw. She is sterile, and she knows whatever this is growing inside her must be removed and destroyed or it will kill both her and the remaining crew. The clip shared here and others available in YouTube actually don’t convey the complete body horror — immediately before Shaw enters this AI-operated surgical pod she is thwarted by the pod’s programming for a default male patient. In spite of her mounting panic and growing pain she must flail at the program to enter alternative commands which will remove the thing growing inside her.

I suspect the clips available in YouTube were uploaded by men, or they would understand how integral to Shaw’s body horror is the inability to simply and quickly tell this surgical pod GET THIS FUCKING THING OUT OF ME RIGHT THE FUCK NOW.

I don’t know if any man (by which I mean cis-man) can really understand this horror. Oh sure, men can realistically find themselves host to things like tapeworms and ticks and other creatures which they can have removed. But the horror of frustration, being occupied by something that isn’t right, not normal, shouldn’t continue, putting its host at mortal risk — and not being able to simply demand it should be removed, or expect resources to avoid its implantation and occupation in one’s self? No. Cis-men do not know this terror.

Now imagine the dull background terror of young women in this country who must listen to white straight male legislators demand ridiculous and offensive hurdles before they will consider funding birth control to prevent sexual transmission of Zika, or fund abortions of Zika-infected fetuses which put their mothers at risk of maternal mortality while the fetuses may not be viable or result in deformed infants who’ll live short painful lives. Imagine the horror experienced by 84 pregnant women in Florida alone who’ve tested positive for Zika and are now being monitored, who don’t know the long-term outcomes for themselves or their infants should their fetuses be affected by the virus.

Body horror, daily, due to occupation not only by infectious agents alien to a woman’s body, but occupation by patriarchy.

I expect to get pooh-poohed by men in comments to which I preemptively say fuck off. I’ve had a conversation this week about Zika risks with my 20-something daughter; she turned down an invitation this past week to vacation with friends in Miami. It’s a realistic problem for her should she accidentally get pregnant before/during/immediately following her trip there.

We also talked about one of her college-age friend’s experiences with Guillain–Barré syndrome. It’s taken that young woman nearly three years to recover and resume normal function. She didn’t acquire the syndrome from Zika, but Guillain–Barré’s a risk with Zika infections. There’s too little research yet about the magnitude of the risk — this vacation is not worth the gamble.

But imagine those who live there and can’t take adequate precautions against exposure for economic reasons — imagine the low-level dread. Imagine, too, the employment decisions people are beginning to make should job offers pop up in areas with local Zika transmission.

What’s it going to take to get through to legislators — their own experience of body horror? Movies depicting body horror don’t seem to be enough.

Wheels
Put these two stories together — the next question is, “Who at VW ordered the emissions cheat device from Bosch before 2008?”

Pretty strong incentives for Volkswagen to destroy email evidence. I wonder what Bosch did with their emails?

Self-driving electric cars are incredibly close to full commercialization based on these two stories:

  • Michigan’s state senate bill seeks approval of driverless cars (ReadWrite) — Bill would change state’s code to permit “the motor vehicle to be operated without any control or monitoring by a human operator.” Hope a final version ensures human intervention as necessary by brakes and/or steering wheel. I wonder which manufacturer or association helped write this code revision?
  • California now committed to dramatic changes in greenhouse gas emissions (Los Angeles Times) — State had already been on target to achieve serious reductions in emissions by 2020; the new law enacts an even steeper reduction by 2030 in order to slow climate change effects and improve air quality.

I don’t know if I’m ready to see these on the road in Michigan. Hope the closed test track manufacturers are using here will offer realistic snow/sleet/ice experience; if self-driving cars can’t navigate that, I don’t want to be near them. And if Michigan legislators are ready to sign off on self-driving cars, I hope like hell the NHTSAA is way ahead of them — especially since emissions reductions laws like California’s are banking heavily on self-driving electric cars.

Google-y-do

  • Google’s parent Alphabet-ting on burritos from the sky (Bloomberg) — No. No. NO. Not chocolate, not doughnuts, not wine or beer, but Alphabet subsidiary Project Wing is testing drone delivery of Chipotle burritos to Virginia Tech students? Ugh. This has fail all over it. Watch out anyhow, pizza delivery persons, your jobs could be on the bubble if hot burritos by drone succeed.
  • API company Apigee to join Google’s fold (Fortune) — This is part of a big business model shift at Google. My guess is this acquisition was driven by antitrust suits, slowing Google account growth, and fallout from Oracle’s suit against Google over Java APIs. Application programming interfaces (APIs) are discrete programming subroutines which, in a manner of speaking, act like glue between different programs, allowing programmers to obtain resources from one system for use in a different function without requiring the programmer to have more than passing understanding of the resource. An API producer would allow Google’s other systems to access or be used by non-Google systems.
  • Google to facilitate storage of Drive content at cloud service Box (PC World) — Here’s where an API is necessary: a Google Drive user selects Box instead of Drive for storage, and the API routes the Drive documents to Box instead of Drive. Next: imagine other Google services, like YouTube-created/edited videos or Google Photo-edited images, allowing storage or use by other businesses outside of Google.

Longread: Digitalization and its panopticonic effect on society
Columbia’s Edward Mendelson, Lionel Trilling Professor in Humanities and a contributor at PC Magazine, takes a non-technical look at the effect our ever-on, ever-observing, ever-connected technology has on us.

Catch you later!

Tuesday: In a Season of Crime

Ride the train, I’m far from home
In a season of crime, none need atone
I kissed your face


— excerpt, Sue (or In a Season of Crime) by David Bowie

Bowie left us an amazing parting shot with his 25th and final album, Blackstar. The cut featured here is a free jazz/jazz-rock fusion work which sounds off-kilter or out of sync, the lyric melody not tracking with rhythm — until one looks at the lyrics as a story of confusion told at the same time as a driving lyric-less and inevitable story beats on at the same time.

Seems like an unintended metaphor for our general election politics.

Back to School, Fool
Guess who’s back in town? A bunch of Congressional lame ducks back from vacation — I mean — work in their districts where they glad-handed at county fairs between bites of deep-fried Twinkies and kissing babies for campaign photo ops.

Get back to work and produce funding for Zika research AND birth control, damn it. Your continued intransigence is costing lives — short, ugly, painful, deformed lives on which you are pitiless and merciless, you fundamentalist let-them-eat-cake hacks. It’s only a matter of time before somebody in your district ends up Zika-infected and pregnant after vacation trip to someplace warm like Miami — or mosquito-bitten during during their day job like lawn care or construction or mail delivery. Researchers are working incredibly hard with the limited funding they’ve had; there’s only so much they can do with inadequate funding. And birth control MUST be available to all who need it. Planned Parenthood can and does hand out condoms, you pathetic slack-handed weasels. Fund them.

STG if I was the president, I’d look at any way possible to trim funding to unusual projects in states with GOP senators and then declare an emergency, pull that trimmed funding to pay for subsidized birth control in the same damned states. With researchers now having found Zika infection may spread by bodily fluids like semen, vaginal fluid, saliva, and tears while documented cases mount, there’s ample grounds to write an executive order during a lame duck session.

Big Oil = Big Bully

The NoDAPL project is bad all around. There’s no good reason for it to proceed.

— The economics of oil supply and demand do not support it; the cost to proceed is simply not supportable.

— The environmental cost of this project and the oil it is intended to carry are untenable; investment of resources private and public should go toward non-fossil fuels.

— The project violates the rights of Native Americans in numerous ways and no good faith effort has been made to address them during planning, let alone now as construction begins. The current and future damage to the Sioux only exacerbates hundreds of years of abuses against their sovereign nation.

— The companies investing in this project including Enbridge cannot assure the safe operation of this pipeline given the history of pipeline leaks across this country. In Enbridge’s case, this foreign-owned corporation has already proven unreliable and opaque in pipeline operations.

— NoDAPL should not proceed for the same reasons Keystone XL pipeline did not proceed: it is not in our country’s best interest.

I don’t know how anyone can look at this bulldozing of land containing buried Native Americans and not see it as a direct, deliberate effort to erase their existence. This is accursed behavior which in no way addresses the needs for alternative energy outlined in the Defense Department’s Quadrennial Review or our nation’s need to secure its people by reducing carbon dioxide output.

Odd Lots

  • Disposal wells in Oklahoma including Osage Nation shut down after earthquake (Tulsa World) — Yet another case where extractive fossil fuel business on Native American tribal lands has been highly problematic. 17 wells were shut down by the EPA after Oklahoma’s M5.6 induced earthquake this weekend; these wells are in addition to 37 other disposal wells shut down this weekend near the quake’s epicenter. Haven’t seen yet whether another earthquake of this magnitude could set off an overdue 500-year magnitude earthquake along Missouri’s New Madrid fault.
  • U.S. district judge denies federal plan to open 1 million acres of central CA public lands for fracking and drilling (IndyBay.org) — Bureau of Land Management didn’t do its homework on environmental risks from fracking, focusing too heavily on drilling instead. Sounds a lot like Army Corp of Engineers’ slap-dash disregard for externalities when it analyzed the NoDAPL, doesn’t it?
  • OK’s earthquake insurance market already under review (Tulsa World) — Insurers have only paid out on 20 percent of earthquake-related claims since 2010; the market has also undergone consolidation and 300-percent rate increases. No word yet on how much damage this weekend’s M5.6 quake or subsequent aftershocks have caused. Hope the public lights a fire under Oklahoma Insurance Commissioner John Doak about his review of the market. It’s grossly unfair the public must bear the cost of risk created by extractive industries as it is.

Longread: Lawsuit against DMCA Section 1201
Johns Hopkins University professor and cryptographer Matthew Green filed suit against the federal government in late July to strike down Section 1201 of the Digital Millennium Copyright Act. The current law prevents security researchers from adequately investigating products. Worthwhile read — this has huge repercussions on our safety and security given how much of the technology around us is copyrighted but leaky as hell and prone to hacking.

Hasta pasta!

Wednesday: If I Had a Heart

Crushed and filled with all I found
Underneath and inside
Just to come around
More, give me more, give me more


— excerpt, If I Had a Heart by Fever Ray

Today’s featured single is from Fever Ray’s eponymous debut album ‘Fever Ray’, the stage name for Swedish singer, songwriter and record producer Karin Elisabeth Dreijer Andersson. If her work sounds familiar, it may be that she and her brother Olof Dreijer also performed as The Knife. Karin’s work is reminiscent of Lykke Li’s and Bjork’s electronic/ambient works, redolent with dark rhythms and layers of deep and high-pitched vocals — very Nordic feminine.

Fever Ray has been very popular with television programmers; the cut featured here is the theme song for History Channel’s Vikings series. It’s also been used in AMC’s Breaking Bad and WB’s The Following. Other songs by Karin as Fever Ray including Keep the Streets Empty for Me have been used by CBS’ Person of Interest and Canadian TV’s Heartbeats as well as a number of films. I’m looking forward to her next work, wondering if it will be just as popular TV and film industry.

Fossil feud

  • TransCanada approval hearing delayed due to protests (Reuters) — Not just U.S. and Native Americans protesting oil pipelines right now; Canada’s National Energy Board deferred this week’s hearings due to security concerns (they say). The board is scheduled to meet again in early October about the planned pipeline from Alberta to Canada’s east coast. There may be more than security concerns holding up these hearings, though…
  • Big projects losing favor with Big Oil (WaPo-Bloomberg) — The ROI on big projects may be negative in some cases, which doesn’t service massive debt Big Oil companies have incurred. They’re looking at faster turnaround projects like shale oil projects — except that these quick-hit projects have poorly assessed externalities which will come back and bite Big Oil over the long run, not to mention the little problem of fracking’s break-even point at $65/barrel.
  • Big Insurance wants G20 to stop funding Big Fossil Fuel (Guardian) — Deadline the biggest insurers set is 2020; by then, Big Insurance wants the G20 nations to stop subsidizing and financing fossil fuels including Big Oil because subsidies and preferential financing skew the true cost of fossil fuels (hello, externalities).
  • Standing Rock Sioux continue their protest against the North Dakota Access Pipeline (Guardian) — Video of the protest at that link. Calls to the White House supporting the Sioux against the DAPL are solicited. Wonder if anybody’s pointing out fracked shale oil is a losing proposition?

Zika-de-doo-dah

  • Adult mosquitoes can transmit Zika to their offspring (American Journal of Tropical Medicine and Hygiene) — Study looked at infected Aedes aegypti and albopictus mosquitoes and found the virus in subsequent larva. My only beef with this study is that Culex species were not also studied; they aren’t efficient carriers of Zika, but they do carry other flavivirus well and there are too many cases with unexplained transmission which could have been caused by infected Culex. Clearly need to do more about pre-hatch mosquito control regardless of species.
  • Three drugs show promise in halting Zika damage in humans (Johns Hopkins Univerity Hub) — Important to note some of the same researchers who demonstrated Zika caused damage in mice brain models earlier this year have now rapidly screened existing drugs to test against mice brain models. The drugs include an anti-liver damage medication (emricasan), an anti-parasitic (niclosamide), and an experimental antivirus drug. The limitation of this research is that it can’t tell how the drugs act across placenta to fetus and whether they will work as well and safely once through the placenta on fetuses. More research (and funding!) is needed.
  • Contraception no big deal, says stupid old white male GOP senator’s staffer (Rewire) — Right. If only McConnell and his staff could experience the panic of being poor and at risk of Zika. Not everybody in Puerto Rico has ready access to the “limited number of public health departments, hospitals, and Medicaid Managed Care clinics,” let alone other states like Texas which has such awful women’s reproductive care in terms of access and funding the maternal mortality rate has doubled in two years, up 27%. Pro-life, my ass. By the way, this lack of access to contraception affects men, too, who may unknowingly be infected with Zika and tranmit it to their sexual partners.

Longread Must-read: Super court
If you haven’t already done so, you need to read this investigative report by Chris Hamby at BuzzFeed. While it answers a lot of questions about the lack of perp walks, it spawns many more.

Hasta luego, compadres!

Friday: Smells Like

With the lights out, it’s less dangerous
Here we are now, entertain us
I feel stupid and contagious
Here we are now, entertain us
A mulatto, an Albino
A mosquito, my libido, yeah


— excerpt, Smells Like Teen Spirit by Nirvana

Been a rough week so I’m indulging myself with some double bass — and because it’s Friday, it’s jazz. This is 2009 Thelonious Monk Competition winner Ben Williams whose ‘Teen Spirit’ is both spirited and minimalist. Check out this set with Home and Dawn Of A New Day, the first embued with a hip-hoppy beatmaking rhythm.

More Shadows on the wall
While Marcy has some questions about the recent alleged Shadow Brokers’ hack of NSA-front Equation Group and malware staging servers, I have a different one.

Why is Cisco, a network equipment company whose equipment appears to have been backdoored by the NSA, laying off 20% of its workforce right now? Yeah, yeah, I hear there’s a downturn in networking hardware sales due to Brexit and the Chinese are fierce competitors and businesses are moving from back-end IT to the cloud, but I see other data that says 50-60% of ALL internet traffic flows through Cisco equipment and there are other forecasts anticipating internet traffic growth to double between now and 2020, thanks in part to more video streaming and mobile telecom growth replacing PCs. Sure, software improvements will mediate some of that traffic’s pressure on hardware, but still…there’s got to be both ongoing replacement of aging equipment and upgrades (ex: Southwest Airlines’ router-fail outage), let alone new sales, and moving the cloud only means network equipment is consolidated, not distributed. Speaking of new sales and that internet traffic growth, there must be some anticipation related to increased use of WiFi-enabled Internet of Things stuff (technical term, that — you know, like Philips’ Hue lighting and Google Nest thermostats and Amazon Echo/Alexa-driven services).

Something doesn’t add up. Or maybe something rolls up. I dunno’. There are comments out on the internet suggesting competitor Huawei is hiring — that’s convenient, huh?

AI and Spy

  • Data security firm working on self-tweeting AI (MIT Review) — The software can generate tweets more likely to illicit response from humans than the average phishing/spearphishing attempt. Seems a little strange that a data security company is working on a tool which could make humans and networks less secure, doesn’t it?
  • Toyota sinks a bunch of cash into AI project at U of Michigan (ReadWrite) — $22 million the automaker pledged to development of self-driving cars, stair-climbing wheelchairs and other mobility projects. Toyota has already invested in similar AI development programs at Stanford in Palo Alto, CA and MIT in Cambridge, MA. Funding academic research appears to be a means to avoid a bigger hit to the corporation’s bottom line if the technologies do not yield commercially viable technology.
  • Steganography developed to mask content inside dance music (MIT Review) — Warsaw University of Technology researcher co-opted the rhythm specific to Ibiza trance music genre. The embedded Morse code buried in rhythm could not be audibly detected by casual listeners as long as it did not distort the tempo by more than 2%.

Sci-like-Fi

  • New theory suggests fifth force of nature possible (Los Angeles Times) — The search for a “dark photon” may have led to a new theory explaining the existence and action of dark energy and dark matter, which together make up 95% of the universe. I admit I need to hunt down a better article on this; this one doesn’t make all the pieces snap into place for me. If you’ve seen a better one, please share in comments.
  • Sound wave-based black hole model may show Hawking radiation at work (Scientific American) — Can’t actually create a real black hole in the lab, but a model like this one created by an Israeli scientist using phonons (not photons) may prove Stephen Hawking was right about information leakage from black holes. The work focuses on the actions of quantum-entangled particle pairs which are separated on either side of the event horizon. Beyond adding to our understanding of the universe, how this work will be used isn’t quite clear. But use of quantum entanglement in cryptography is an important and growing field; I wouldn’t be surprised to see this finding shapes cryptographic development.
  • Pregnant women’s immune system response may affect fetus’ neurological system (MedicalXpress via Phys.org) — While an expectant mother’s immune system may prevent a virus from attacking her fetus, the protective process may still affect the fetus long term. Research suggests that some neurological disorders like schizophrenia and autism may be associated with maternal infections pre-birth.

Late adder: Travel Advisory issued for pregnant women to avoid Miami Beach area according to CDC — Five more cases of Zika have been identified and appeared to have originated in the newly identified second Zika zone, this one east of Biscayne Bay in the Miami Beach area. The initial Zika zone was on the west side of Biscayne Bay. The CDC also discouraged pregnant women and their sex partners from traveling to Miami-Dade County as a whole; the county has now had a total of 36 cases of Zika.

In the video in the report linked above, FL Gov. Rick Scott pokes at the White House about additional Zika assistance, but Scott previously reduced spending on mosquito control by 40%. Now he’s ready to pay private firms to tackle mosquito spraying. Way to go, Republican dirtbag. Penny wise, pound foolish, and now it’s somebody else’s job to bat cleanup.

Longread: Stampede at JFK
A firsthand account of the public’s stampede-like reaction to a non-shooting at New York’s JFK International Airport. To paraphrase an old adage, if all you have is a gun, everything looks and sounds like a shooting.

Let go of your fear and let the weekend begin.

Friday: The Immoral Minority

While philosopher Slavoj Žižek isn’t everybody’s cup of quirky tea, he’s got a valid point in this video.

The right-wing has abandoned its claim to be the Moral Majority.

Don’t mistake this as a validation of the Democratic Party here in the U.S.; they are only earning a majority in terms of politics, and in no small part by being the “Not GOP” party. With its leadership cozying up to war criminals, climate denialists and fossil fuel-based polluters, and general denigrators both of human rights and the public commons, they are not the Moral Majority by default.

But an unorganized left in this country rejects the right-wing’s ethical decay implicitly underpinning the Republican Party. The left rejects those values which undermine democracy — misogyny, racism and marginalization of other minorities, the ongoing subversion of individuals’ rights to promote the interests of corporations.

A true Moral Majority won’t support a social contract undermining democracy by limiting life, liberty, and happiness’ pursuit to a narrow few. It’s well past time for the broader left to coalesce into an organized entity based upon the belief that all humans are created equal and deserving a more perfect union.

Zapped by Zika

  • “ZIKA VIRUS | Days since White House funding request: 186 | Funding response from Congress: $0 | Zika cases in US and territories: 8,580” (Tweet, Dan Diamond/Politico)
  • Peter robbed to pay Paul: DHHS pulls money from other projects to fund Zika vaccine research (Reuters) — Lacking new dedicated funding from Congress, U.S. Department of Health and Human Services squeezed out $81 million and spread it into Zika vaccine research, with $34 million of that to the National Institutes of Health and $47 million to the Biomedical Advanced Research and Development Authority (BARDA). The white House had asked for $1.9 billion last fall for Zika, but that amount was pared down by 42%; Republicans then objected to any of the remaining portion going to Planned Parenthood, putting Democrats in a bind. Access to birth control is critically important to preventing Zika’s spread; access to abortion could prevent the birth of severely deformed infants who will live short, utterly miserable, and expensive lives.
  • Arthrogryposis — congenital joint defects — associated with Zika during pregnancy (The BMJ) — Dislocated and or misshaped knees, ankles, elbows, hips appeared in children born with other neurological defects found in Zika-infected fetuses. Further research is necessary to prove both the virus is causal and learn the mechanism by which the virus inflicts this damage in utero. The patients had been tested for other known causes of arthrogryposis — toxoplasmosis, cytomegalovirus, rubella, syphilis, and HIV. All were negative.
  • First infant death due to Zika reported in Texas (KHOU) — The infant’s mother traveled to El Salvador during pregnancy where it is believed she contracted the virus.
  • Zika virus case confirmed in Monroe County, Michigan (Detroit Free Press) — But the method of infection is not clear (what?!). County health and state officials are working toward mosquito surveillance.

Wheels and steals

  • Millions of vehicles made from 1995 on vulnerable to keyless-remote hacking (USENIX) — Researchers at University of Birmingham and Kasper & Oswald GmbH presented a paper at the USENIX 2016 conference, showing more than 20 years’ worth of VW Group vehicles are hackable using inexpensive Arduino-based RF transceiver technology. Alfa Romeo, Chevrolet, Peugeot, Lancia, Opel, Renault, Ford and other makes relying on the Hitag2 access security method are similarly at risk. Researchers also looked at after-market keyless entry remotes for these and other vehicles; the cars for which these worked were also vulnerable. All vehicles tested appear to be those made for the European market, but the research noted the radio frequency differences — 315 MHz band in North America and the 433 MHz or 868 MHz band in Europe — used in remotes. The paper’s research team notified VW in November 2015 of their results; NXP Semiconductor, a manufacturer of Hitag2 remote technology, was also notified. NXP had already informed customers of the vulnerability in 2012 and has already improved device security.
  • Volkswagen suppressed news about keyless remote insecurity since 2013 (Bloomberg) — The same researchers from University of Birmingham and Kasper & Oswald GmbH had originally approached NXP Semiconductor and VW with their work in 2012 and 2013, respectively. VW sued and blocked release of their work; the paper was released this past week at USENIX only “after lengthy negotiations” and the removal of a single sentence which car thieves could use to easily crack the keyless remotes. A number of suspicious automobile thefts over the years may have relied on hacking remotes; will insurance companies look into these thefts and demand recovery from VW?
  • DOE grants Ford $6M for fuel cell research (Detroit Free Press) — Existing fuel cell technology has been too expensive for successful commercialization; the grant will be used to develop cheaper technology competitive with battery and internal combustion engines.

Longread: Geopolitics
FiveBooks.com interviewed former state department official and senior fellow at the Council on Foreign Relations, Jennifer M. Harris, about geopolitics. She discusses the topic and offers five book recommendations about the same. Harris is the co-author of recently released War by Other Means: Geoeconomics and Statecraft. Given her work as U.S. National Intelligence Council staff followed by work on economics under then-Secretary of State Hillary Clinton, this interview might offer a preview to future statecraft.

Friday Jazz
It’s still Friday somewhere according to my clock. Try French performer Zaz, stage name for Isabelle Geffroy. If you like this ditty, preview more of her work on her channel on SoundCloud.

It’s been a hectic week here; next week doesn’t look any better, but I’ll aim to be here on Monday. Have a relaxing weekend!

Bringing out the Dead: What We Know about Zika Virus Effect on Human Tissue

[(A) Control neurosphere (B) Zika-infected neurosphere Source: Science, 13MAY2016 http://science.sciencemag.org/content/352/6287/816.full]

[(A) Control neurosphere
(B) Zika-infected neurosphere
Source: Science, 13MAY2016
http://science.sciencemag.org/content/352/6287/816.full]

Because unproven claims persist that chemical exposure — specifically the pyridine-based pesticide pyriproxyfen — causes the birth defects seen in children born to women exposed to Zika virus, I am bringing out the dead, laying out the bodies.

By ‘bodies’ I mean sharing here pictures of cells you see in the embedded photos from a peer-reviewed study published this May.

In these images you’ll see the damage done to human tissue in lab conditions.

No pyriproxyfen was present.

How Researchers Studied Zika
This is the methodology researchers used:

1) The researchers used human stem cells to create neurospheres — the kind of cells which turns into nerve and brain tissue in an actual embryo.

2) They set aside control samples of neurospheres which were not infected.

3) They infected test samples neurospheres with Brazilian Zika virus.

4) They observed the changes in the infected neurospheres.

5) They compared them to the uninfected control samples.

6) They wrote and published a report on their findings.

The image above is the best example from their report of the difference between Zika-infected cells and the uninfected test samples.

What Researchers Found in this Study
In short, Zika inhibits, damages, and kills infected neurospheres.

This is what we can expect to happen to a fetus’ brain or nerve tissues when infected by Zika under the right conditions during early pregnancy.

[(A) Control mock-infected organoid (B) Zika-infected organoid (damage noted at arrows; growth was also inhibited)]

[(A) Control mock-infected organoid
(B) Zika-infected organoid (damage noted at arrows)]

What Else Researchers Found in this Study
The researchers also conducted a very similar test on human brain organoids. These are not single neurospheres but neuro-tissue grown from stem cells so that they form a model like a tiny brain. Not a brain, a tissue-based model of a brain.

They used the same six steps above using a mock-infected model, a Zika-infected model, and a dengue virus-infected model. (Dengue fever is caused by a flavivirus — the same family of viruses to which Zika and yellow fever belong.) Researchers found Zika virus caused similar destructive damage on these larger models while limiting their growth; they did not find the same damage or destruction in the dengue-infected models and none in the mock-infected control models. Zika alone damaged neurological tissue models.

Researchers also studied neural stem cells (NSCs) — the simplest neuro tissue model — and found similar results in which the Zika virus killed off NSCs. Studying NSCs, neurospheres, and organoids, the researchers observed Zika’s actions on different stages of neuro tissue maturity. In each of these models, from the simplest (NSCs) to the most complex (organoids), Zika was destructive.

[ZIKV (Zika virus) induces death in human neurospheres. These micrographs show the ultrastructure of mock- and ZIKV-infected neurospheres after 6 days in vitro. (A) Mock-infected neurosphere showing cell processes and organelles. (B) ZIKV-infected neurosphere showing a pyknotic nucleus, swollen mitochondria, smooth membrane structures, and viral envelopes (arrow). (C) Viral envelopes on the cell surface (arrows). (D) Swollen mitochondria. (E) Viral envelopes inside the endoplasmic reticulum (arrows). (F) Viral envelopes close to smooth membrane structures (arrows).]

[ZIKV (Zika virus) induces death in human neurospheres. These micrographs show the ultrastructure of mock- and ZIKV-infected neurospheres after 6 days in vitro.
(A) Mock-infected neurosphere showing cell processes and organelles.
(B) ZIKV-infected neurosphere showing a pyknotic nucleus, swollen mitochondria, smooth membrane structures, and viral envelopes (arrow).
(C) Viral envelopes on the cell surface (arrows).
(D) Swollen mitochondria.
(E) Viral envelopes inside the endoplasmic reticulum (arrows).
(F) Viral envelopes close to smooth membrane structures (arrows).]

Other Research on Zika Using Mouse Tissue
Three other studies published in May this year using mice or mouse tissues likewise showed evidences of neurological tissue and brain damage or growth suppression when infected by Zika virus. The studies came from research facilities in Brazil, China, and the U.S. — and in each study, pyriproxyfen was not included. The Zika-infected specimens showed damage and the control specimens did not.

The study from Brazil at the University of São Paulo also included research using human stem cells, comparing a Brazilian strain of Zika against an African strain:

Beltrão-Braga, Muotri, and their colleagues also grew brain organoids from human stem cells and infected these in vitro models with the Brazilian and African strains of the virus. In the human mini brains, both strains of the virus caused cell death, but the Brazilian strain appeared to also interfere with the formation of cortical layers. The virus didn’t replicate in the brain organoids grown from chimpanzee stem cells, suggesting it may have adapted to human tissue, the researchers noted in their paper.

Emphasis mine. Research published earlier showed Zika has already mutated rapidly after arriving in Brazil, with at least nine variants found inside the last two years.

What’s Next in Zika Research
What researchers don’t yet know, for starters: How Zika works — how does it damage or kill cells? When exactly does the virus do the most damage? What mechanisms interfere with Zika’s operations and can they be used in vaccines or drug therapy? What makes Zika different from dengue or other flavivirus? What does Zika do to adult neuro tissue to cause Guillain-Barre Syndrome? Which adults are most at risk? Will the different mutations in Brazil respond differently to vaccines? How long can humans carry live Zika virus? Has the virus mutated and become transmissible by bodily fluids or aerosol? These are just a few of the questions we still have about Zika.

There are some good guesses about Zika’s mechanisms — like this hypothesis focusing on vitamin A storage in the liver, which also suggests Zika may negatively affect liver cells (yet another avenue of research needed). But will a vaccine targeting this activity work for other flavivirus, too? What if this guess is wrong; are there other approaches we’ve yet to hear about?

We won’t have any of these answers in a reasonable period of time if we don’t have adequate funding.

It’s not just birth defects we are talking about here, either. Look at the damage in those images again; this virus not only damages fetal nerve and brain tissue, it kills fetuses. Infants born with Zika-related defects may be blind and may lead short, painful lives. And it may kill and maim adults, too, if they develop a serious case of Zika-related Guillain-Barre Syndrome.

Let’s not bring out any more Zika dead.

(Note: Forgive me for the simplistic terms used in this post if you have a background in science. I had to make this as brief and succinct as possible for those who don’t have that background.)
___________

Source:
Zika virus impairs growth in human neurospheres and brain organoids
BY PATRICIA P. GARCEZ, ERICK CORREIA LOIOLA, RODRIGO MADEIRO DA COSTA, LUIZA M. HIGA, PABLO TRINDADE, RODRIGO DELVECCHIO, JULIANA MINARDI NASCIMENTO, RODRIGO BRINDEIRO, AMILCAR TANURI, STEVENS K. REHEN
SCIENCE13 MAY 2016 : 816-818
Zika virus infection in cell culture models damages human neural stem cells to limit growth and cause cell death.
URL: http://science.sciencemag.org/content/352/6287/816.full

Zika Studies Using Mice:
F. Cugola et al., “The Brazilian Zika virus strain causes birth defects in experimental models,” Nature, doi:10.1038/nature18296, 2016.

C. Li et al., “Zika virus disrupts neural progenitor development and leads to microcephaly in mice,” Cell Stem Cell, doi:10.1016/j.stem.2016.04.017, 2016.

J. Miner et al., “Zika virus infection during pregnancy in mice causes placental damage and fetal demise,” Cell, doi:10.1016/j.cell.2016.05.008, 2016.

Friday: The End of the World

I wake up in the morning and I wonder
Why ev’rything is the same as it was
I can’t understand, no, I can’t understand
How life goes on the way it does


— excerpt, The End of the World, written by Arthur Kent and Sylvia Dee

Jazz version of this song first released by Skeeter Davis in 1962 performed here by Postmodern Jukebox’s Scott Bradlee and band with Niia’s vocals.

A few people in my timeline have asked over the last several months, “Is this the end of the world, or does it just feel like like it?”

It’s the end of something, that’s for sure.

Z is for Zika

I can’t make this clear enough to Congress: you’re playing with lives here, and it’s going to be ugly. It will affect your families if anyone is of childbearing age. I haven’t seen anything in the material I’ve read to date that says definitively studies are underway to verify transmission from Brazil’s Culex quinquefasciatus to humans. There’s a study on the most common U.S.’ Culex pipiens species which showed weak transmission capabilities, but once it’s proven quinquefasciatus can transmit, it’s just a matter of time before more effective pipiens pick up and transmit the virus, and they may already have done so based on the two cases in Florida. GET OFF YOUR BUTTS AND FUND ADEQUATE RESEARCH PRONTO — or risk paying for it in increased health care and other post-birth aid for decades.

Still Brexin’ it

Clean-up duty

  • Looking for MH370 in all the wrong places — for two years (IBTimes) — Bad suppositions? Or misled? Who knows, but the debris found so far now suggests the plane may have glided across the ocean in its final moments rather than plummeting nose first.
  • Enbridge settles $177 million for 2010 oil pipeline rupture (ICTMN) — Seems light for the largest ever oil spill inside the continental U.S., and their subsequent half-assed attempts to clean up the mess. Check the photo in the story and imagine that happening under the Straits of Mackinac between Lakes Huron and Michigan. How did it take them so long not to know what had happened and where?
  • Broadband companies now have a real competitive threat in Google Fiber (USAToday) — It’s beginning to make a dent in some large markets where Google Fiber’s 1Gb service has already been installed. But it is slow going, don’t expect it in your neighborhood soon. You’re stuck with your existing slowpoke carriers for a while longer.
  • Cable lobby counters FCC pressure on set-top boxes (Ars Technica) — Sure, they’ll yield to the FCC on set-top boxes, but they won’t offer DVR service and each cable provider with 1 million subscribers or more will be responsible for their own apps. Cable lobby claims copyright issues are a concern with the DVR service; is that a faint whiff of MPAA I smell?

Beach-bound longread
Check out this piece in WIRED: David Chang’s Unified Theory of Deliciousness. I’m hungry after reading just a portion of it.

Hasta luego, mi amigas. Catch you Monday if the creek don’t rise.

Tuesday: Crazy

Come on now, who do you, who do you, who do you, who do you think you are,
Ha ha ha bless your soul
You really think you’re in control

Well, I think you’re crazy
I think you’re crazy
I think you’re crazy
Just like me


— excerpt, Crazy by Gnarls Barkley

Why’d I pick this song today? Oh, no reason. Just kind of popped into my head while I was reading through my aggregators.

Ahem. Anyhow…not much time again today, lot of hurry-up-and-wait stuff demanding my time.

Turkey curry buffet

Quick lap around the track

  • BREXIT: IMF cuts UK’s growth forecast (The Guardian) — Really, what the hell did the Leavers expect? Put the brain trust and creative sector into a tailspin as so many are immigrants, and ask them to sustain or expand growth? Completely unrealistic.
  • US-UK RELATIONS: Presser today with Johnson and Kerry (The Guardian) — You watch it. I can’t even with that lying hack Johnson — he spun more crap right to journos’s faces. And nobody takes these two to task over most recent bombings in Syria or Yemen.
  • ZIKA: CDC studying unusual case of UT caretaker infected by Zika (CDC.gov) — The elderly Utah man who died of Zika recently somehow infected his caretaker with the virus without sexual contact. Mosquitoes may have been involved, but UT isn’t home to known carriers Aedes aegypti and albopictus species. The deceased, however, had a viral load 100,000 times greater than the average Zika patient. What?!
  • EARTHQUAKES: Earthquake swarm continues in San Benito County, California (NBC Bay Area) — 24 quakes in 24 hours based on report published about two hours ago. The affected area is west of Silicon Valley and the San Andreas fault line.
  • POLICE REFORMS: Hire more women: one of several known solutions to police racism and abuse (Yes! Magazine) — Take note of the gender of police accused and charged with abuse and killing of unarmed civilians. Body cameras, greater diversity matching community, and openness to research also included in solutions.

That’s all I have time for now. See you tomorrow!

Monday: Magic

You want some magic this Monday to start your week? Check this short film Vorticity by Mike Olbinski. If you can launch it in full screen or cast it to a television, even better, and I hope you have decent speakers for the sound. Mike’s wife is a saint, a wholly different kind of magic off screen to support a guy who does this stuff.

Under the gun here today, too much real world stuff to check off my To Do List. Only a quick list of stuff worth looking at.

Kudos
Bravo to Michigan’s Rep. Dan Kildee (D-Flint Township) who filed the Families of Flint Act last week to provide $1.5 billion in relief funding for water system repairs, additional health care, monitoring and education, as well as economic development to support the struggling city. Co-sponsors include U.S. Reps. Sander Levin (D-Royal Oak), Debbie Dingell (D-Dearborn MI), Brenda Lawrence (D-Southfield MI), and John Conyers (D-Detroit), along with 167 other House Dems.

Lean on House GOP members to do the right thing and support this bill when they are next in session in August.

Leftovers
Couple of things screwed up or left unfulfilled before Congress left town:

Quick List

Catch you tomorrow, gotta’ dash!